Co-Amoxiclav

Amoxicillin + clavulanic acid

Antibiotics- antibacterial drugs

Anti-infective drugs> Antibacterial drugs> Penicillins > Aminopenicillins

Powder for preparation of oral suspension Co-amoxiclav 156, containing:

Amoxicillin 125mg/5ml (as Trihydrate)

Clavulanic Acid 31.25mg/5ml (as Potassium salt)

Powder for preparation of Co-amoxiclav 228 oral suspension, containing:

Amoxicillin 200mg/5ml (as Trihydrate)

Clavulanic Acid 28.5mg/5ml (as Potassium salt)

Powder for preparation of Co-amoxiclav 312 oral suspension, containing:

Amoxicillin 250mg/5ml (as Trihydrate)

Clavulanic Acid 62.5mg/5ml (as Potassium salt)

Powder for preparation of Co-amoxiclav 457 oral suspension, containing:

Amoxicillin 400mg/5ml (as Trihydrate)

Clavulanic Acid 57mg/5ml (as Potassium salt)

Co-amoxiclav 375 coated tablets, containing:

Amoxicillin 250mg/5ml (as Trihydrate)

Clavulanic Acid 125mg/5ml (as Potassium salt)

Co-amoxiclav 625 coated tablets, containing:

Amoxicillin 500mg/5ml (as Trihydrate)

Clavulanic Acid 125mg/5ml (as Potassium salt)

Co-amoxiclav is a bactericide which prevents the construction of the bacterial cell wall causing the death of the bacteria that is growing and dividing. Moreover, clavulanic acid in co-amoxiclav inhibits beta-lactamase.

Co-amoxiclav is a drug that is used to treat infections of the lower respiratory tract, otitis media, sinusitis, skin infections and urinary tract infections. It is also used for sore throats and colds. The dosage of Co Amoxiclav varies for children and adults. Common doses of co-amoxiclav include co-amoxiclav 375 and 625.

It is better not to take co-amoxiclav during pregnancy and breastfeeding. Amoxicillin is rapidly excreted in breast milk and its safety during breastfeeding has not been proven yet. Clavulanate is also secreted in milk. Co-amoxiclav should be administered with caution during breastfeeding.

Monitor the patient for signs of hypersensitivity reactions during the treatment with co-amoxiclav.

Co-amoxiclav can be taken before or after food.

Consult your doctor about how many days co-amoxiclav should be taken, though always remember that the course of treatment with this medicine should be completed carefully.

If a person has diabetes and takes this drug, it is better to control the glucose in the urine while taking co-amoxiclav.

Before takin co-amoxiclav suspension, shake it well.

Drug interactions of co-amoxiclav include:

Taking probenecid (one of the medicines used to treat gout) simultaneously reduces the renal excretion of co-amoxiclav leading to the increase in its blood level.

BCG vaccine

Cholera vaccine

Doxycycline

Minocycline

Mycophenolate

Tetracycline

Typhoid vaccine

In case of kidney failure, you should take co-amoxiclav with the doctor’s opinion.

Patients who are highly allergic to any type of Penicillins or cephalosporins should avoid taking co-amoxiclav.

All medicines have possible unwanted side effects along with the therapeutic effect, although not all of these side effects can be seen in the same person. However, if any of them occurred, consult your doctor.

The most serious side effect of co-amoxiclav is diarrhea, in case of which, it is necessary to consult a doctor to continue the treatment.

Feeling weak and lethargic is another common side effect, which is usually caused by long-term use of this medication. The reason for weakness and lethargy is due to the loss of beneficial intestinal bacteria that produce B vitamins in the body.

Another side effect of co-amoxiclav suspension is the possibility of stains on the teeth, which can be removed by brushing.

People who have phenylketonuria should never take co-amoxiclav suspension since it may contain aspartame, which is very dangerous for these patients.

According to the different forms of co-amoxiclav, the recommendations of this drug are administered based on the pharmaceutical form.

Co-amoxiclav tablets

Preferably take the medicine on an empty stomach (at least 1 hour before or 2 hours after a meal), though in case of digestive problems, you can take it after your meal.

If you have a history of allergy to antibiotics, inform your doctor.

Inform your doctor or pharmacist if diarrhea occurs.

Taking this medicine affects the results of your clinical tests, so before having a test, inform your doctor of taking it.

It is better not to breastfeed the child during the treatment of the mother with this medicine.

Due to the reduction of the effectiveness of contraceptives when taken at the same time as this drug, women of reproductive age who are treated with this drug should use a non-hormonal prevention method with the doctor’s advice.

If you have diabetes, control your blood glucose regularly and more carefully.

Long-term watery diarrhea with heartburn and up to several weeks after treatment may be a rare side effect of this medication. In this case, see a doctor and avoid self-medication.

Co-amoxiclav sachet

Prepare the contents of each package of medicine at one time according to the instructions on the package.

Preferably take the medicine on an empty stomach (at least 1 hour before or 2 hours after a meal), but if you have a digestive problem, you can take the medicine after your meal. You can also mix the medicine in cold liquids, milk or powdered milk and take it immediately.

Inform your doctor or pharmacist if diarrhea occurs.

Due to the reduction of the effect of contraceptives when taken at the same time as this medicine, women of reproductive age who are treated with this medicine should use a non-hormonal prevention method with the doctor’s advice.

If you have a history of allergy to antibiotics, inform your doctor.

Taking this medicine affects the results of your clinical tests, so before having a test, inform your doctor of taking it.

If you have diabetes, control your blood glucose periodically and more carefully.

Long-term watery diarrhea with heartburn and up to several weeks after treatment may be a rare side effect of this medication. In this case, see a doctor and avoid self-medication.

Co-amoxiclav suspension

Prepare the medicine with cooled boiled water according to the instructions on the medicine package.

When preparing the medicine, add water in two steps so that it reaches the exact amount after mixing with the medicine.

Shake the prepared solution before use and store it in the refrigerator for up to 10 days.

Measure and take the medicine exactly as prescribed by the doctor at each time.

Preferably take the medicine on an empty stomach (at least 1 hour before or 2 hours after a meal), though in case of digestive problems, you can take the medicine after a meal. You may also mix the medicine in cold liquids, milk or powdered milk and take it immediately.

In case of diarrhea, inform your doctor or pharmacist.

Due to the reduction of the effect of contraceptives when taken at the same time as this medicine, it is necessary to use other prevention methods during treatment with this drug.

If you have a history of allergy to antibiotics, inform your doctor.

Taking this medicine affects the results of your clinical tests, so before having a test, inform your doctor of taking it.

If you have diabetes, control your blood glucose periodically and more carefully.

Long-term watery diarrhea with heartburn that may last for several weeks after treatment is one of the rare side effects of this medication. In this case, see a doctor and avoid self-medication.

After preparing co-amoxiclav suspension (people may know as co-amoxiclav syrup too), the medicine can be stored in the refrigerator for up to 10 days.

Co-amoxiclav tablets should be stored in closed containers that are resistant to light and at a temperature lower than 24 degrees Celsius.

For preparation of co-amoxiclav suspension (co-amoxiclav syrup), cooled boiled water should be used. If un-boiled water is used, the antibiotic effect will be lost. First, the powder should be shaken completely so that it is separated and does not stick together, then the boiled water which is cooled is added until the mark line on the container. Finally, shake the glass well to form a suspension. The container of co-amoxiclav suspension should be kept stationary for half an hour, during which the level of the medicine will fall below the target line. Then add some water to it again to return to the specified level. Co-amoxiclav suspension (co-amoxiclav syrup) should be kept in the refrigerator. Shake co-amoxiclav suspension thoroughly before each use. Co-amoxiclav suspension can be used up to a maximum of 14 days after preparation.